Nan Wang Selected Research

taspine

5/2014	A novel taspine derivative, HMQ1611, suppresses adhesion, migration and invasion of ZR-75-30 human breast cancer cells.
9/2013	A novel taspine derivative suppresses human liver tumor growth and invasion in vitro and in vivo.
6/2012	A novel taspine derivative, HMQ1611, inhibits breast cancer cell growth via estrogen receptor α and EGF receptor signaling pathways.
1/2012	Tas13D inhibits growth of SMMC-7721 cell via suppression VEGF and EGF expression.
11/2011	Antitumor activity of taspine by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo.
9/2011	Activity of taspine isolated from Radix et Rhizoma Leonticis against estrogen-receptor-positive breast cancer.
7/2011	[Effect of taspine derivatives on human liver cancer SMMC7721].

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Nan Wang Research Topics

Disease

206	Neoplasms (Cancer) 12/2022 - 12/2002
65	Inflammation (Inflammations) 12/2022 - 05/2008
46	Breast Neoplasms (Breast Cancer) 05/2022 - 06/2008
40	Infections 01/2022 - 11/2005
39	Atherosclerosis 09/2022 - 01/2003
23	Hypersensitivity (Allergy) 06/2022 - 10/2013
21	Type 2 Diabetes Mellitus (MODY) 01/2022 - 07/2005
20	Neoplasm Metastasis (Metastasis) 01/2022 - 11/2013
19	Hepatocellular Carcinoma (Hepatoma) 12/2022 - 05/2006
17	Carcinogenesis 09/2022 - 12/2012
17	COVID-19 06/2022 - 01/2020
15	Hypoxia (Hypoxemia) 10/2022 - 10/2013
14	Body Weight (Weight, Body) 08/2022 - 08/2010
13	Wounds and Injuries (Trauma) 03/2022 - 08/2014
13	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 03/2003
12	Thrombosis (Thrombus) 10/2022 - 01/2012
12	Glioma (Gliomas) 10/2022 - 09/2009
12	Anaphylaxis (Anaphylactic Shock) 06/2022 - 12/2016
12	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 01/2014
12	Stomach Neoplasms (Stomach Cancer) 12/2021 - 10/2014
11	Insulin Resistance 03/2022 - 03/2015
11	Alzheimer Disease (Alzheimer's Disease) 02/2022 - 05/2009
11	Heart Failure 01/2022 - 06/2009
10	Cognitive Dysfunction 11/2022 - 12/2015
10	Hemorrhage 10/2022 - 08/2017
10	Obesity 08/2022 - 11/2015
10	Necrosis 03/2022 - 05/2006
10	Asthma (Bronchial Asthma) 01/2022 - 01/2016
10	Leukemia 12/2021 - 06/2006
10	Hypertension (High Blood Pressure) 12/2021 - 03/2003
10	Osteonecrosis (Kienbock's Disease) 04/2021 - 08/2013
9	type 2C Congenital disorder of glycosylation 06/2022 - 01/2018
9	Carcinoma (Carcinomatosis) 01/2022 - 05/2009
9	Pneumonia (Pneumonitis) 01/2022 - 07/2010
9	Lung Neoplasms (Lung Cancer) 05/2021 - 01/2013
9	Cardiomegaly (Heart Hypertrophy) 01/2021 - 06/2009
8	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2022 - 05/2014
8	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 05/2022 - 04/2014
8	Fibrosis (Cirrhosis) 01/2022 - 06/2010
8	Huntington Disease (Huntington's Disease) 01/2022 - 05/2011
8	Hyperglycemia 01/2022 - 02/2012
8	Atherosclerotic Plaque (Atheroma) 01/2022 - 10/2011
8	Myocardial Infarction 11/2021 - 06/2009
8	Ischemia 08/2021 - 12/2005
8	Pain (Aches) 01/2021 - 11/2012
8	Hypertrophy 11/2020 - 01/2011
8	Melanoma (Melanoma, Malignant) 01/2018 - 10/2005
7	Colitis 07/2022 - 04/2016
7	Glioblastoma (Glioblastoma Multiforme) 01/2022 - 09/2012
7	Rheumatoid Arthritis 01/2022 - 05/2017
7	Human Influenza (Influenza) 01/2022 - 04/2008
7	Osteosarcoma (Osteogenic Sarcoma) 12/2021 - 03/2016

Drug/Important Bio-Agent (IBA)

85	Proteins (Proteins, Gene)FDA Link 09/2022 - 11/2005
44	Pharmaceutical PreparationsIBA 12/2022 - 07/2007
42	Biomarkers (Surrogate Marker)IBA 10/2022 - 02/2009
38	MicroRNAs (MicroRNA)IBA 09/2022 - 06/2009
33	CytokinesIBA 09/2022 - 12/2005
30	CholesterolIBA 01/2022 - 01/2003
28	Glucose (Dextrose)FDA LinkGeneric 08/2022 - 07/2005
26	Biological ProductsIBA 01/2022 - 09/2006
25	VaccinesIBA 01/2022 - 11/2005
24	Messenger RNA (mRNA)IBA 10/2022 - 08/2009
20	Long Noncoding RNAIBA 05/2022 - 01/2017
17	RNA (Ribonucleic Acid)IBA 09/2022 - 06/2012
17	LipidsIBA 01/2022 - 07/2008
17	EnzymesIBA 01/2020 - 10/2005
16	Transcription Factors (Transcription Factor)IBA 01/2022 - 12/2002
15	CalciumIBA 06/2021 - 08/2011
15	Peptides (Polypeptides)IBA 02/2021 - 11/2005
14	AntioxidantsIBA 10/2022 - 08/2010
13	Interleukin-6 (Interleukin 6)IBA 04/2022 - 03/2014
13	Immunoglobulin E (IgE)IBA 01/2022 - 10/2014
12	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2022 - 05/2006
12	Therapeutic UsesIBA 01/2022 - 06/2008
11	Adenosine Triphosphate (ATP)IBA 06/2021 - 05/2008
11	Connexin 43 (Connexin43)IBA 01/2021 - 09/2009
10	Insulin (Novolin)FDA Link 12/2022 - 03/2015
10	Phosphotransferases (Kinase)IBA 01/2022 - 01/2012
10	SteroidsIBA 04/2021 - 08/2013
10	HDL LipoproteinsIBA 01/2020 - 06/2004
9	LigandsIBA 12/2022 - 11/2005
9	fibroblast growth factor 21IBA 10/2022 - 09/2017
9	Monoclonal AntibodiesIBA 01/2022 - 01/2014
9	ATP-Binding Cassette Transporters (ABC Transporters)IBA 12/2020 - 09/2003
9	myocardinIBA 12/2017 - 01/2011
8	CateninsIBA 09/2022 - 03/2018
8	Interleukin-17 (Interleukin 17)IBA 07/2022 - 07/2010
8	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 06/2022 - 11/2017
8	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2022 - 07/2011
8	Apolipoproteins E (ApoE)IBA 01/2022 - 10/2006
8	Small Interfering RNA (siRNA)IBA 11/2021 - 01/2011
8	Antiviral Agents (Antivirals)IBA 09/2021 - 02/2007
8	AntibodiesIBA 01/2021 - 09/2013
7	ProteomeIBA 01/2022 - 08/2008

Therapy/Procedure

91	Therapeutics 12/2022 - 07/2005
23	Drug Therapy (Chemotherapy) 09/2022 - 07/2007
11	Immunotherapy 01/2022 - 07/2008
9	Radiotherapy 05/2022 - 06/2017
9	Transplantation 08/2021 - 03/2010
8	Chinese Traditional Medicine (Traditional Chinese Medicine) 03/2021 - 08/2014